The Structural Heart Programme at CVSKL is a one stop centre for screening, diagnosis, surveillance and treatment for all heart valve disease.
Heart Valve Disease
Structure & function of the heart
Our heart consists of four chambers. There are two upper chambers called the left and right atrium, and two lower chambers called the left and right ventricles. Each chamber of the heart has one valve, making it 4 valves in total. The valves allow the blood to move through the heart in single direction only.
The valves are called the aortic valve, pulmonary valve, tricuspid valve and mitral valve.
mitral valve 、 tricuspid valve are located between the atria and the ventricles.
aortic valve 、 pulmonary valve are located between the ventricles and the major blood vessels leaving the heart.
Types of heart valve disease
When heart valves become diseased or damaged, they may not completely open or close. Your heart will find it hard to pump properly. As a result, your heart will pump even harder to make sure there is enough blood circulating around your body. As the heart muscles become overworked, other heart problems follow.
Stenosis 、 regurgitation are the two types of heart valve diseases. Some people may even have a combination of both.
Stenosis occurs when your valve does not open properly. The heart becomes strained as the pressure and blood can back up.
Regurgitation, also known as an insufficiency, occurs when your valve does not close properly. Blood leaks through the valve rather than flow in one direction only. Also, the heart is forced to work harder to maintain enough blood circulating around your body.
Aortic Valve Stenosis
What is aortic valve stenosis (AS)?
Valves in the heart act like windows to ensure blood flows from one chamber/structure to the next in a single direction.
Aortic valve stenosis is a disease described by the narrowing of the valve opening due to congenital abnormality, age-related degeneration and rheumatic valve disease. This will interrupt the ability of the heart to pump blood out to supply the body. Over time, the heart function will progressively weaken.
Patients with moderate to severe AS may not show any symptom at all. However, in the late stages, patient may complain of chest pain (angina), shortness of breath (dyspnea) and even fainting spells (syncope). These symptoms are made worse with physical activity.
What are the causes of aortic valve stenosis?
Several conditions can cause your aortic valve to thicken. Among them are:
What are the aortic stenosis symptoms?
When you have mild aortic valve stenosis, you may never feel any symptoms. For serious cases, there are some symptoms worth noting. They include:
What is TAVI ?
TAVI, an acronym for Transcatheter Aortic Valve Implantation (or Replacement, TAVR), is a minimally invasive procedure to replace the diseased aortic valve as opposed to the conventional heart surgery.
With advancements in device technology, non-invasive imaging, increasing operator expertise and proper patient selection, the outcome of TAVI may be comparable but less morbidity, shorter hospital stays and resumption of normal activities in much shorter time.
How does TAVI Work?
The prosthetic aortic valve is mounted within a special catheter. This catheter is carefully advanced from the groin or shoulder artery and delivered across the diseased valve.The procedure is performed under the guidance of x-ray imaging and transesophageal echocardiography.
Once the valve is optimally positioned, it will be deployed. This new valve will immediately take over the function of the diseased valve.
This TAVI procedure may be conducted under general anaesthesia or conscious sedation.
Benefits of TAVI
• Shorter length of stay in ICU and hospital
• Faster or almost no need for wound recovery
• Less bleeding
• Earlier ambulation and return to normal quality of life
Complication of TAVI
• Electrical Conduction abnormalities that may require permanent pacemaker implantation
• Perivalvular Leak
• Obstruction of the coronary arteries
• Possible complications related to Vascular Access site
Mitral Valve Regurgitation
What’s mitral valve regurgitation?
Mitral regurgitation is backward blood leakage through the mitral valve each time the left ventricle contracts.
A leaking mitral valve causes blood to flow in two directions during the contraction. Some blood flows through the aortic valve (as it should normally) and some blood flows back into the atrium.
What’s the problem that results from mitral regurgitation?
Leakage can increase the blood volume and pressure in the left atrium. This increased pressure can increase pressure in the veins coming from the lungs emptying into the heart (pulmonary veins).
Increased pressure in the case of severe regurgitation cause fluid build-up or congestion in the lungs.
What are the causes of mitral valve regurgitation?Possible causes of mitral regurgitations are:
• Mitral prolapse
• Damaged tissue cords
• Rheumatic fever
• Heart attack
• Congenital heart defects
What are the mitral valve regurgitation symptoms?
Some people who have mitral valve disease may not experience any symptoms for many years. Depending on its severity and how quickly the condition progresses, signs and symptoms of mitral valve regurgitation include:
• Abnormal heart sound (heart murmur) heard through a stethoscope
• Shortness of breath (dyspnea), worsened by physical activity or when lying down
• Heart palpitations — sensations of a rapid, fluttering heartbeat
• Swollen feet or ankles
MitraClip Transcatheter Mitral Valve Repair
What is MitraClip?
The MitraClip is a device delivered to the heart through a small incision made in the blood vessel in the groin area. The heart continues beating during the procedure and does not require a heart-lung bypass machine as in open heart surgery.
During the mitral valve repair procedure, a catheter (a thin, flexible plastic tube) is inserted through the patient’s skin in the groin area and is guided through the femoral vein to the affected area of the heart.
Then, a catheter that holds the MitraClip device goes in through the first catheter so that the MitraClip can be guided into place and attached to the leaflets of the mitral valve. Once the clip is properly placed and securely attached, it is deployed and the catheters are removed.
Benefits of MitraClip
• Improved quality of life.
• Improved symptoms.
• Reduced chance of hospitalization.
• Likely reduction in heart size.
• Improvement heart shape.
• Reduction in mitral regurgitation.
• Avoidance of high surgical risk.
Complication of MitraClip
• Possible multiple use of MitraClip
• Vascular access site-related complications
Know Your Treatment Options at CVSKL
CVSKL is one of the very few Cardiovascular Centres of Excellence in Malaysia capable of performing TAVI & Mitraclip procedure. Our Heart Team comprises of a group of experienced and internationally renowned cardiologists, cardiothoracic surgeons, vascular surgeons, cardiac anaesthetists and cardiac imaging specialists who work cohesively and collaboratively to ensure the best outcomes for our TAVI & Mitraclip patients.
One of the in-house interventional cardiologists is also a TAVI proctor and he is renowned for his pioneering work on TAVI procedure in Malaysia.